Neuroendocrine signalling research peptide for controlled laboratory studies.
- Dose
- 10 mg
- Batch
- 268011
Kisspeptin-10
Kisspeptin-10 (human), KISS1 (112-121) amide / metastin (45-54) amide · YNWNSFGLRF
For research purposes only — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Neuroendocrine signalling research peptide for controlled laboratory studies.
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- Lab
- Janoshik Analytical
- Purity
- 99.208%
- Methods
- HPLC · LC-MS
- Tested
- Oct 6, 2026
For laboratory research use only. Not for human consumption.
Technical specifications
- Type
- Peptide
- Scientific name
- Kisspeptin-10 (human), KISS1 (112-121) amide / metastin (45-54) amide
- Amino acids
- 10
- Sequence
- YNWNSFGLRF
- Molecular weight
- 1302.4 g/mol
- Formula
- C63H83N17O14
- CAS
- 374675-21-5
- Origin
- C-terminal decapeptide (residues 112-121) of the human KISS1 precursor, identical to metastin(45-54); C-terminally amidated (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2) and the shortest fully active ligand of KISS1R/GPR54.
- Lyophilized (powder)
- -20°C · stable long-term; keep sealed, desiccated and protected from light
- Reconstituted
- 2-8°C · use within 30 days; aliquot and hold at -20°C to avoid repeated freeze-thaw
- Room temperature
- Lyophilized powder tolerates brief ambient shipping excursions of a few days without meaningful loss. In solution it does not: the decapeptide is proteolytically labile and reconstituted material left at room temperature degrades over hours to days, so vials should be returned to refrigeration immediately after handling.
Peer-reviewed research
Published research and registered trials involving this compound. Provided for educational reference only — none of it is a claim about this product.
- NatureMetastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptorOhtaki T, Shintani Y, Honda S et al.2001DOI: 10.1038/35079135PMID: 11385580
- Journal of Biological ChemistryThe metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54Kotani M, Detheux M, Vandenbogaerde A et al.2001DOI: 10.1074/jbc.M104847200PMID: 11457843
- Journal of Biological ChemistryAXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1Muir AI, Chamberlain L, Elshourbagy NA et al.2001DOI: 10.1074/jbc.M102743200PMID: 11387329
- Journal of Cell ScienceKisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblastsBilban M, Ghaffari-Tabrizi N, Hintermann E et al.2004DOI: 10.1242/jcs.00971PMID: 15020672
- Journal of Clinical Endocrinology & MetabolismKisspeptin resets the hypothalamic GnRH clock in menChan YM, Butler JP, Pinnell NE et al.2011DOI: 10.1210/jc.2010-3046PMID: 21470997
- Journal of Clinical Endocrinology & MetabolismKisspeptin-10 is a potent stimulator of LH and increases pulse frequency in menGeorge JT, Veldhuis JD, Roseweir AK et al.2011DOI: 10.1210/jc.2011-0089PMID: 21632807
- International Journal of EndocrinologyChanges in the Responsiveness of the Hypothalamic-Pituitary-Gonadal Axis to Kisspeptin-10 Administration during Pubertal Transition in BoysNabi G, Ullah H, Khan S et al.2018DOI: 10.1155/2018/1475967PMID: 30046307
- Current Medicinal ChemistryKisspeptin and its Current Clinical Status-A Systematic ReviewVelmurugan H, Mannava AS, Thangaraju P, Neelambaran K2025DOI: 10.2174/0109298673251224230919093656PMID: 38265397
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